Author Guidelines

Environmental Toxicology and Chemistry (ET&C) welcomes submissions dealing with all phases of environmental toxicology, environmental chemistry, non-chemical ecological stressors, human heatlh from environmental exposures, remediation and restoration, and hazard/risk assessment. This includes subjects dealing with the harmful effects of a wide range of chemical, biological, and physical stressors on organisms, populations, communities, and ecosystems. Manuscripts and related materials should be submitted through ET&C's electronic submission system.

Please review the following information for details on submitting manuscripts to and publishing with ET&C.

Content Published in ET&C

Environmental Chemistry

Papers should emphasize how chemistry is applied to measuring, assessing, or predicting chemical fate (abiotic and biological transformations) and environmental exposure (bioavailability, bioaccumulation) including indoor environments. The work should provide insights into toxicological responses of exposed organisms (including humans). The applicability of the work to environmental assessment, environmental toxicology, or ecological risk assessment must be clear. Papers on analytical methods must demonstrate meaningful and useful advancements over existing methods, potential to influence current practice, and application to environmental samples and environmental assessment in general. Theoretical or modeling studies oriented toward predicting environmental behavior, chemical properties, or toxicity must show direct applicability to environmental or ecological risk assessment.

Environmental Toxicology

Papers may deal with the harmful effects of chemical stressors on organisms, populations, communities, and ecosystems. Papers that use data or models to elucidate mechanisms and advance the ability to extrapolate toxicological information across species, chemicals, levels of biological organization, or ecosystems are particularly desirable. In addition, papers that show the interactions of multiple stressors and their resulting effects are also a priority. Studies that report in vivo toxicity endpoints intended to establish exposure- or dose-response relationships to be used in hazard or risk assessment should include analytical confirmation of exposure or dose concentrations. The exception to this requirement is on confirmation of nanomaterial concentrations that are in complex matrices, such as soils, sediments and periphyton, because the state-of-the-science makes this exceedingly difficult.

Non-Chemical Ecological Stressors

Papers may deal with the harmful effects of a wide range of biological and physical stressors that may (or may not) interact with naturally occurring or anthropogenic chemicals to affect organisms, populations, communities, and ecosystems. This includes stressors such as alterations of habitat, climate change, and invasive species. Papers that show the interactions of multiple stressors and their resulting effects are also a priority.

Remediation and Restoration

Papers should deal with the remediation and restoration of contaminated sites, where the focus is the removal of chemical contaminant exposures in the environment. Ideally, studies should incorporate indirect and/or direct measures of biological exposures and improvement but also may include meeting a regulatory-driven contaminant level. Field-based investigations and monitoring studies are preferred, but laboratory mechanistic pilot studies may be acceptable if based on realistic scenarios that relate field exposures to adverse effects.

Human Health from Environmental Exposures

Papers should relate environmental exposures to chemicals with potential risks for adverse health effects in humans. Papers addressing human toxicology mechanisms and risks must encompass realistic environmental exposure. Ideally, studies would incorporate pathway-based approaches focused on integrated assessment of chemical risk (i.e., across human and non-human taxa). Occupational work place exposure and effects studies are inappropriate.

Hazard/Risk Assessment

Manuscripts should describe hazard or risk assessments, or provide methods or models to use in such assessments. Case studies must have sufficient scope and impact to be of interest to a broad audience. While most hazard and risk assessments focus on metals and synthetic organic chemicals, we are particularly interested in assessments that also include other cumulative stressor effects, including interactions with non-chemical stressors, such as alteration of habitat, climate change, or invasive species. Hazard/risk assessments should focus on the science of hazard/risk assessments; papers delving deeply into policy, regulation, value judgments, or public, social, or legal issues should be submitted to SETAC's second journal, Integrated Environmental Assessment and Management (IEAM).

Inappropriate Content

ET&C does not publish papers on certain topics. These include: 1) papers that focus on human health toxicology, unless they are tied closely to exposures to environmental stressors or extrapolated to responses in wildlife or other aspects of ecotoxicology; 2) remediation technologies; 3) papers that focus on treatment processes dealing with effluents, wastes, and contaminants; 4) occupational exposure in humans; and 5) pollution prevention.

Results of studies with high site-specificity, such as toxicity testing of a particular effluent, must have substantial application beyond the immediate environmental setting. Papers that primarily report outcomes of standard toxicity tests, or routine biochemical, molecular, or histological measures, with an additional organism, test system, or chemical are subject to particular scrutiny to ensure that their scientific impact warrants publications in ET&C.

Types of Manuscripts

Original Articles (8000 words) must report research on topics of scientific significance and environmental importance showing new experimental data, new interpretations of existing data, or new theoretical analyses of environmental phenomena. Submissions should not be submitted elsewhere, other than as an abstract or an oral or poster presentation. Students should indicate to their advisors and their university that they are publishing a paper based on their thesis or dissertation and that the document should not be posted online.

Short Communications (4400 words) should present concise statements representing either a preliminary report or a complete accounting of a significant research contribution. Brief methods papers will be accepted in this category.

Critical Reviews (10 000 words) assess areas of environmental science and technology research literature of current importance in the field. Submissions should increase readers’ knowledge through perceptive comparisons, thorough literature coverage, and a clear identification of research needs.

Letters to the Editor (2200 words) may concern any scientific topic relevant to the purposes of the journal, including critical discussion of ET&C papers published within the past 24 months. Letters that concern a previously published paper, if deemed appropriate for publication, will be sent to the original authors for a single response. Two ET&C editors will review Letters to the Editor.

Focus Articles are part of a regular series of timely articles intended to sharpen our understanding of current and emerging topics of interest to the scientific community at large. Focus Articles should be written in a succinct, magazine style. We encourage authors to limit the reference list to only the most critical references, to include sidebar material or text boxes that highlight important aspects of your paper, and to use color figures, tables, and/or photos. Focus articles undergo the same rigorous peer review to which all ET&C papers are subjected. It will be edited for a more journalistic style, an active voice, and more descriptive headings than ET&C Original Articles. It will also implement the use of sidebar material or boxes of text that highlight important aspects of your paper. If have a suggestion for a Focus Article, please contact the editor-in-chief, G.A. Burton.

Perspectives are part of a regular series designed to discuss and evaluate potentially competing viewpoints and research findings on current environmental issues. Two or 3 authors will present their thoughts and opinions on an issue of national and international importance. We prefer that the 3 sectors of the SETAC tripartite (academia, government, business) are represented, but this is not required. Each Perspectives column will undergo the same rigorous peer review to which all ET&C papers are subjected.

Special Sections and Special Issues

Special section and special issues group together papers resulting from a workshop or papers on a related topic. To propose a special section or special issue contact the editor-in-chief or the editorial office. For more information, see the guidelines for proposing a special section or workshop series).

Manuscript Preparation

We understand that formatting a manuscript for submission and publication is a time-consuming process. To simplify the process, ET&C no longer requires authors to fully format manuscripts during the initial submission. Paying attention to a few guidelines will help ensure that your manuscript can be understood and reviewed more quickly. For your initial submission, please see the Abbreviated Manuscript Preparation guidelines.

If your manuscript is found acceptable pending revisions, you will be asked at the revision stage to format your manuscript according to ET&C's full guidelines for preparing a manuscript and adhering to CSE style and format (see Full Manuscript Preparation Guidelines).

Manuscript Submission

All manuscripts and related materials should be submitted to the ET&C electronic submission system. Per journal policy, if a manuscript is rejected after the first round of reviews, it can be submitted for 1 additional round of review. If it is rejected a second time, resubmission is not permitted.

Please include the following information and elements with your submission:

Cover Letter

Each manuscript must be accompanied by a cover letter describing how the work advances understanding in the field and how the manuscript fits within the journal's aims and scope. This letter should also describe other manuscripts the authors have published or intend to publish on closely related work and the relationship of the current work to these other manuscripts.

Manuscript and Graphics, and Additional Data

All text, tables, and figures must be submitted according to ET&C style (see Manuscript Preparation guidelines).

Documentation of Unpublished, Cited Works

Copies of cited or related manuscripts not yet in print must be part of the submission package, along with supplemental information files to be posted in conjunction with the article.

Conflict of Interest Reporting

Potential conflicts of interest must be reported at the time the manuscript is submitted. Research funding or other support from outside the authors' stated affiliation must be disclosed within the manuscript.

Statement of Protocol Approval for Animal Research

Research involving animals (vertebrates, cephalopods) must conform to the SETAC Code of Ethics and to contemporary guidelines for the care and use of animals (for example, or The manuscript should include a statement of protocol approval from an Institutional Review Board and an Institution Animal Care and Use Committee.

Data Repository Statement

ET&C requires authors to provide a Data Availability Statement clarifying whether data, associated metadata, and calculation tools are available through an online repository or supplemental files, available from the authors or a third party, or unavailable (with reasoning). Note that all data (including data that are not publicly available) must be made available to the editor and reviewers during the review process, if requested, but will be kept in confidence. Failure to provide data as requested may be grounds for rejection. See the full data transparency policy.

Automated Data Repository Deposition with figshare

ET&C is part of an initiative to streamline submission, deposition, and permanent archiving of data files in association with published articles. This is a free service for all ET&C authors.

figshare offers an online repository for supplemental data files, such as data tables, small CSVs, images, PDFs, etc., that are otherwise not suitable for deposition into large government and institutional data repositories. With figshare, ET&C authors have the ability to make their supplemental data files citable by DOI and discoverable to the public. Although figshare does not replace Supplemental Data, we encourage authors to designate data files that would have previously been submitted as Supplemental Data as “Data Files” during the submission process.

Authors choosing to include data files for figshare should create a “Data Accessibility” section in their manuscript, after the Acknowledgment section, which provides brief descriptions (e.g., the equivalent of legends) for each of your figshare files.

The process for publishing data files—following acceptance of your manuscript—is as follows:

  1. During the submission process,files designated as “Data Files” from the pull-down menu in the submission system will be automatically deposited into the ET&C figshare repository. See examples here.

  2. The data files will inherit metadata from your manuscript with no effort required on your part.

  3. Your data files on figshare will be assigned a single DOI, making them uniquely identified and citable.

  4. The link and DOI for your files will be automatically added to your published article, in the “Data Accessibility” section. An example is available here. Files will be made public on figshare once the article publishes on Wiley Online Library.

For additional information and FAQs, please refer to this page.

Manuscript Processing


Each manuscript is assigned to an editor with expertise in the field discussed, who in turn sends it to a minimum of 2 reviewers. Reviewers give evaluations, suggest improvements, and recommend acceptance or rejection of the paper. Reviewing should be completed within 2 months. If reviewers disagree, the paper may be sent to an additional reviewer. The editor sends a decision letter and the critiques of reviewers to the corresponding author, along with a detailed list of editorial issues to be amended or improved.

The decision letter from the editor will give instructions for uploading the revised manuscript to Manuscript Central. Include a response to reviewers that describes the disposition of each of the reviewers' suggestions, item by item. Indicate the page and line number of the revised text and highlight the sections that have been changed on the revised manuscript to aid the editor in determining acceptability. Authors wishing to reject all or specific suggestions should state their reasons. Take care to include all necessary changes on the final revised manuscript.

As publishing scientists, we all benefit from an effective peer-review process. To ensure that the peer-review process continues to be efficient for ET&C, we ask the corresponding author of each accepted manuscript to review for the journal. Please login to to verify that your contact information is up-to-date and select keywords specific to your area of research.

Plagiarism and iThenticate

ET&C uses iThenticate software to screen submissions for content published elsewhere. By submitting your manuscript to ET&C you accept that your manuscript may be screened against previously published work, and you may be asked to clarify similar work appearing elsewhere. ET&C reserves the right to reject submissions that contain content judged to have appeared elsewhere. This includes, in certain cases, papers published online, including theses and dissertations.

Document (cite and reference) any ideas or words taken from the intellectual efforts of yourself or others, whether published or unpublished. This includes citations to your own previously published work.

Language Assistance

The journal's staff is unable to provide extensive editorial assistance regarding English usage and grammar. If necessary, authors are asked to seek appropriate editorial assistance before submitting their manuscript for review. See Wiley-Blackwell’s English Language Editing Service. For additional resources, see;; or Using an English language editing service can help to ensure your paper is clearly written in standard, scientific English language, but does not guarantee that it will be accepted for publication. Authors are responsible for all costs associated with these services.

Manuscript Publication

Copyright Transfer Agreement

Authors must sign the SETAC copyright transfer agreement before their paper can be published. Individual company copyright transfer agreements may not be substituted. If your paper is accepted, the author identified as the formal corresponding author for the paper will receive an email prompting him or her to login into Author Services, where he or she will be able to complete the license agreement on behalf of all authors on the paper via the Wiley Author Licensing Service (WALS).

If the OnlineOpen option is not selected, the corresponding author will be presented with the copyright transfer agreement (CTA) to sign. The terms and conditions of the CTA can be previewed in the samples associated with Licensing Info & FAQs.

If the OnlineOpen option is selected, the corresponding author will have a choice of the following Creative Commons License Open Access Agreements (OAA):

  • Creative Commons Attribution License OAA
  • Creative Commons Attribution Non-Commercial License OAA
  • Creative Commons Attribution Non-Commercial -NoDerivs License OAA

To preview the terms and conditions of these open access agreements, please visit the Creative Commons License information page hosted on Wiley Author Services.

If you select the OnlineOpen option and your research is funded by The Wellcome Trust and members of the Research Councils UK (RCUK), you will be given the opportunity to publish your article under a CC-BY license supporting you in complying with Wellcome Trust and Research Councils UK requirements. For more information on this policy and the Journal’s compliant self-archiving policy, please visit:


Authors are responsible for obtaining permission to reprint a previously published table, figure, or excerpt of more than 250 words and for submitting written permissions with their manuscript. Acknowledgement alone is not sufficient; if in doubt, obtain permission. Permissions should be submitted quickly after your paper is accepted to avoid any delays in publication. Authors should exercise customary professional courtesy in acknowledging intellectual properties such as patents and trademarks. Authors wishing to reprint illustrations or text previously published in ET&C should contact

Page Proofs and Publication

Authors are able to track their manuscript through the production process by registering for Author Services. Immediately after acceptance, but prior to any editing or formatting, manuscripts will be assigned a DOI and made available for viewing at After manuscripts have been edited for adherence to journal style and typeset, page proofs will be emailed directly to the corresponding author. Authors are responsible for proofreading. Limit changes to correcting printer's errors when possible. Return the corrected proof to Wiley-Blackwell within 48 hours. Save a copy of the corrected proof for reference. The ET&C editorial office also reviews page proofs and may submit additional changes consistent with ET&C's style. Once the page proofs have been finalized, the final version of record will be published online as an Early View article and assigned to an issue.


Authors should inform the editorial staff if they discover any significant errors in their final published manuscripts. If necessary, corrections will be published.

Author Fees

When a manuscript is accepted for publication and sent in for typesetting, it is expected to be in its final form. Excessive revisions may result in additional charges.

Color and Page Charges

Authors are no longer required to pay for color reproduction of figures or page charges.


The corresponding author will receive a PDF at no additional charge. Authors of accepted manuscripts will be invited to send by e-mail a PDF offprint of their final published paper direct from the publisher to up to 10 individuals located anywhere in the world free of charge. Additional reprints may be ordered at